Daily Fantasy: Strategy and lineup picks for NFL Week 16

This specific four-man build takes up a huge portion of salary but there are plenty of sub-$20 running backs available in Week 16 to be able to jam in the top two wide receivers on the slate.[Play in Yahoo's Week 16 Million Dollar Baller DFS contest]Over the last month, Cooper Kupp and Justin Jefferson are tied for the lead league with 12 targets per game.In that span, the Rams have thrown at the fourth-highest rate in neutral game script and their passing game should feast against a Vikings defense ranked in the bottom two in schedule-adjusted fantasy points allowed to both quarterbacks and wide receivers. Odell Beckham helps lower the average salary per player in this stack and has seemingly hopped into the No. 2 role in LA with 21 percent of targets and a quarter of air yards over the last month.[12 Days of Winning from Yahoo Daily Fantasy: Join special holiday contests]How popular Jefferson ends up on Sunday may hinge on the availability of Adam Thielen, but no matter how tournament players approach it, building around Minnesota’s passing game will offer some leverage off of Alexander Mattison, who figures to be the most popular player on the slate with Dalvin Cook landing on the COVID list.Of the QB/WR stacks with the five highest ceilings, according to 4for4, this is the only one that has a cumulative salary below $60. Atlanta has a respectable 24.25-point implied total in a game that is surprisingly stackable on both sides.Low-salary running backs dominate the value reports this week, opening up salary for cash game players to comfortably target some of the higher-end passing games on the slate.QB: Justin Herbert, Joe BurrowRB: Alexander Mattison, Justin Jackson, Ronald Jones, Josh Jacobs, James Robinson, Cordarrelle PattersonWR: Cooper Kupp, Justin Jefferson, Diontae Johnson, Antonio Brown, Amon-Ra St. Brown, Byron Pringle, Mecole HardmanTE: Mark Andrews, Foster Moreau, Kyle Pitts, Dawson Knox, Noah GrayDEF: Eagles, Chargers, Falcons, RaidersThis article originally appeared in its full form on 4for4.comTJ is a former full-time poker player who has been playing fantasy football for more than a decade.