the University of San Diego
Runner’s World
Cell
Mark Chapman
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That’s why endurance training “teaches” your muscles to run more efficiently, Chapman said, because the genes are adapting to the stimuli they’re given, so that they will perform better on subsequent, similar activities.For example, these genes will change how much oxygen is delivered to your muscles, so you have enough fuel for endurance exercise, Chapman said.
As said here by https://www.runnersworld.com/news/a33218634/how-endurance-exercise-impacts-genes-study/