Michigan Medicine
JCI Insight
APS
6-gingerol.”Lupus
Ramadan Ali
Jason Knight
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Ann Arbor
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The authors of the study set out to “determine the extent to which ginger-derived compounds might function as a natural suppressor of aberrant neutrophil hyperactivity.”To investigate, the scientists assessed the effects of 6-gingerol on mice with lupus. This result indicates that the ginger compound might break the cycle of inflammation and potentially work as a treatment.Overall, the authors conclude:[T]his study is the first to demonstrate a protective role for ginger-derived compounds in the context of lupus and importantly provides a potential mechanism for these effects via phosphodiesterase inhibition and attenuation of neutrophil hyperactivity.This preclinical study has laid an exciting foundation for the team.
As said here by Toni Matthews-El